通过近红外光谱法无创测量前臂血流量和耗氧量。
Noninvasive measurement of forearm blood flow and oxygen consumption by near-infrared spectroscopy.
作者信息
De Blasi R A, Ferrari M, Natali A, Conti G, Mega A, Gasparetto A
机构信息
Istituto di Anestesiologia e Rianimazione, I Università di Roma, Italy.
出版信息
J Appl Physiol (1985). 1994 Mar;76(3):1388-93. doi: 10.1152/jappl.1994.76.3.1388.
We applied near-infrared spectroscopy (NIRS) for the simultaneous measurement of forearm blood flow (FBF) and oxygen consumption (VO2) in the human by inducing a 50-mmHg venous occlusion. Eleven healthy subjects were studied both at rest and after hand exercise during vascular occlusion. FBF was also measured by strain-gauge plethysmography. FBF measured by NIRS was 1.9 +/- 0.8 ml.100 ml-1.min-1 at rest and 8.2 +/- 2.9 ml.100 ml-1.min-1 after hand exercise. These values showed a correlation (r = 0.94) with those obtained by the plethysmography. VO2 values were 4.6 +/- 1.3 microM O2 x 100 ml-1.min-1 at rest and 24.9 +/- 11.2 microM O2 x 100 ml-1.min-1 after hand exercise. The scatter of the FBF and VO2 values showed a good correlation between the two variables (r = 0.93). The results demonstrate that NIRS provides the particular advantage of obtaining the contemporary evaluation of blood flow and VO2, allowing correlation of these two variables by a single maneuver without discomfort for the subject.
我们应用近红外光谱法（NIRS），通过诱导50 mmHg的静脉闭塞来同时测量人体前臂血流量（FBF）和耗氧量（VO2）。对11名健康受试者在血管闭塞期间的静息状态和手部运动后进行了研究。还通过应变片体积描记法测量了FBF。通过NIRS测量的静息状态下的FBF为1.9±0.8 ml·100 ml-1·min-1，手部运动后为8.2±2.9 ml·100 ml-1·min-1。这些值与通过体积描记法获得的值具有相关性（r = 0.94）。静息状态下的VO2值为4.6±1.3 microM O2×100 ml-1·min-1，手部运动后为24.9±11.2 microM O2×100 ml-1·min-1。FBF和VO2值的散点图显示这两个变量之间具有良好的相关性（r = 0.93）。结果表明，NIRS具有获得血流量和VO2同步评估的独特优势，通过单一操作即可使这两个变量相关联，且受试者不会感到不适。
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