Lown B, Verrier R L, Blatt C M
Am J Cardiol. 1978 Sep;42(3):425-8. doi: 10.1016/0002-9149(78)90937-2.
Sequenital mechanical pulsing of the chest wall with three stimuli failed to induce arrhythmias in normal dogs. After coronary arterial occlusion, this technique evoked in 11 of 12 animals repetitive ventricular tachycardia in 2. These responses corresponded closely to those elicited by electrical testing. In four conscious animals after recovery from myocardial infarction, precordial pulsing induced repetitive ventricular arrhythmias. The type of arrhythmia produced depended on the degree of prematurity of the third pulse in the sequence. The use of precordial mechanical stimulation can perhaps be modified and adapted as a method of detecting persons at high risk for sudden cardiac death.
对正常犬进行胸壁的连续机械脉冲刺激,施加三种刺激均未能诱发心律失常。冠状动脉闭塞后,该技术在12只动物中的11只诱发了室性心动过速,其中2只出现反复性室性心动过速。这些反应与电测试所引发的反应密切对应。在4只心肌梗死后恢复的清醒动物中,心前区脉冲诱发了反复性室性心律失常。所产生的心律失常类型取决于序列中第三个脉冲的提前程度。心前区机械刺激的应用或许可以进行改进并作为一种检测心脏性猝死高危人群的方法。