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在23摄氏度或28摄氏度饲养的大鼠中棕色脂肪组织的产后发育

Post-natal development of brown adipose tissue in the rat bred at 23 degrees C or 28 degrees C.

作者信息

Beauvallet M, Portet R, Blancher G, Solier M

出版信息

Arch Int Physiol Biochim. 1978 Feb;86(1):145-52. doi: 10.3109/13813457809069891.

Abstract

In view to study the effects of thermal environment on the development and the thermogenic activity of interscapular brown adipose tissue (BAT), young rats born at 23 degrees C or 28 degrees C were sacrificed at 1, 3, 7, 11, 14 or 21 days after birth. The rate of increase in animal weight was quite the same at both temperatures up to the 14th day. The development of BAT and its contents in lipids, in water and in noradrenaline indicate that the energetic activity of the tissue is greatly stimulated in rats kept at 23 degrees C up to the 11th day. It is concluded that in rats bred in the habitual thermal conditions (23 degrees C), the occurrence of non shivering thermogenesis (NST) is important during the period of ten days after birth; in the following period NST could be progressively replaced by other thermoregulatory processes.

摘要

为了研究热环境对肩胛间棕色脂肪组织(BAT)发育及产热活性的影响,将出生于23摄氏度或28摄氏度环境下的幼鼠在出生后1、3、7、11、14或21天处死。在第14天之前,两种温度下动物体重的增加速率相当。BAT的发育及其脂质、水分和去甲肾上腺素含量表明,在23摄氏度环境下饲养至第11天的大鼠中,该组织的能量活性受到极大刺激。得出的结论是,在习惯热环境(23摄氏度)中饲养的大鼠,出生后十天内非寒战产热(NST)的发生很重要;在随后的时期,NST可能会逐渐被其他体温调节过程所取代。

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