Bude R O, Rubin J M, Platt J F, Adler R S
Department of Radiology, University of Michigan Medical School, Ann Arbor.
Angiology. 1994 Jul;45(7):605-11. doi: 10.1177/000331979404500703.
Recent studies have investigated the detection of significant arterial stenoses through identification of the "pulsus tardus" phenomenon in Doppler waveforms obtained distal to the stenosis. The etiology of this phenomenon, however, has not yet been determined. Using an in vitro model based upon an electrical circuit analogy, the authors had as their objective to determine whether the compliance of the vessel wall immediately distal to a stenosis, in conjunction with the stenosis, is the cause of pulsus tardus. For a constant stenosis, it was found that the degree of pulsus tardus, as quantitated by the acceleration index, increased as the compliance of the poststenotic segment increased. It is concluded that pulsus tardus distal to an arterial stenosis is likely due to the compliance of the normally distensible artery, in conjunction with the stenosis. Pathological conditions that alter the compliance of the poststenotic segment may affect the degree of pulsus tardus, perhaps limiting its usefulness for upstream stenosis detection.
最近的研究通过识别狭窄远端获得的多普勒波形中的“迟脉”现象来研究显著动脉狭窄的检测。然而,这种现象的病因尚未确定。作者使用基于电路类比的体外模型,旨在确定狭窄远端紧邻的血管壁顺应性与狭窄共同作用是否是迟脉的原因。对于恒定的狭窄,发现用加速度指数定量的迟脉程度随着狭窄后段顺应性的增加而增加。得出的结论是,动脉狭窄远端的迟脉可能是由于正常可扩张动脉的顺应性与狭窄共同作用所致。改变狭窄后段顺应性的病理状况可能会影响迟脉程度,这或许会限制其在上游狭窄检测中的效用。