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马运动神经元病的流行病学

Epidemiology of equine motor neuron disease.

作者信息

Mohammed H O, Cummings J F, Divers T J, de la Rua-Domenech R, de Lahunter A

机构信息

College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.

出版信息

Vet Res. 1994;25(2-3):275-8.

PMID:8038800
Abstract

Equine motor neuron disease (EMND) is a newly recognized neurodegenerative disorder of bulbospinal motor neurons in the horse. We conducted a case-control study to identify intrinsic factors associated with the risk of this disorder. Seventy-four cases and 160 controls were assembled. Controls included horses diagnosed with equine protozoal myelitis, equine degenerative myeloencephalopathy, and cervical stenotic myelopathy during the same time period as the cases. Logistic regression analysis was used to evaluate the association of each hypothesized factor while simultaneously controlling for the effect of other factors. Factors found to be significantly associated with the risk of the disease were breed and age of the horse. Quarterhorses are at a higher risk in comparison to other breeds of horse.

摘要

马运动神经元病(EMND)是一种新发现的马的延髓脊髓运动神经元神经退行性疾病。我们进行了一项病例对照研究,以确定与该疾病风险相关的内在因素。共收集了74例病例和160例对照。对照包括在与病例相同时间段内被诊断患有马原生动物脊髓炎、马退行性脊髓脑脊髓病和颈椎狭窄性脊髓病的马。采用逻辑回归分析来评估每个假设因素的关联,同时控制其他因素的影响。发现与疾病风险显著相关的因素是马的品种和年龄。与其他品种的马相比,夸特马患病风险更高。

相似文献

1
Epidemiology of equine motor neuron disease.马运动神经元病的流行病学
Vet Res. 1994;25(2-3):275-8.
2
Intrinsic, management, and nutritional factors associated with equine motor neuron disease.与马运动神经元病相关的内在、管理和营养因素。
J Am Vet Med Assoc. 1997 Nov 15;211(10):1261-7.
3
Risk factors associated with equine motor neuron disease: a possible model for human MND.
Neurology. 1993 May;43(5):966-71. doi: 10.1212/wnl.43.5.966.
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Epidemiologic evidence for clustering of equine motor neuron disease in the United States.
Am J Vet Res. 1995 Nov;56(11):1433-9.
5
Incidence and risk factors of equine motor neuron disease: an ambidirectional study.
Neuroepidemiology. 1995;14(2):54-64. doi: 10.1159/000109779.
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A multicenter case-control study of risk factors for equine protozoal myeloencephalitis.马属动物原虫性脑脊髓炎危险因素的多中心病例对照研究。
J Am Vet Med Assoc. 2007 Dec 15;231(12):1857-63. doi: 10.2460/javma.231.12.1857.
7
Associations of sex, breed, and age with cervical vertebral compressive myelopathy in horses: 811 cases (1974-2007).马的性别、品种和年龄与颈椎压迫性脊髓病的相关性:811例病例(1974 - 2007年)
J Am Vet Med Assoc. 2008 Nov 1;233(9):1453-8. doi: 10.2460/javma.233.9.1453.
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Association between plasma vitamin E concentration and the risk of equine motor neuron disease.
Vet J. 1997 Nov;154(3):203-13. doi: 10.1016/s1090-0233(97)80021-4.
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[Equine motor neuron disease (EMND). A case report].
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Factors associated with the development of equine degenerative myeloencephalopathy.与马退行性脊髓脑病变发展相关的因素。
Am J Vet Res. 1990 Aug;51(8):1300-5.

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