Yoshitomi A, Sato A, Imokawa S, Suganuma H, Tamura R, Suda T, Yagi T, Iwata M, Hayakawa H, Chida K
Second Department of Internal Medicine, Hamamatsu University School of Medicine.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Apr;32(4):373-7.
A 44-year-old female was admitted to our hospital for the purpose of undergoing hysterectomy for removal of multiple uterine tumors. A chest X-ray film obtained on admission revealed a solitary nodule in the right lung field. The resected specimen containing the uterine tumors revealed well differentiated leiomyoma with no nuclear atypia or mitotic figures. The resected specimen from the pulmonary tumor revealed histologic findings similar to those of the uterine myomas, being devoid of any signs of mitosis. Similar cases have been reported as so-called benign metastasizing leiomyoma, and are generally regarded as low grade malignancy or leiomyomatosis. However, we consider this case to have had a primary pulmonary leiomyoma associated with uterine myoma since the pulmonary lesion was solitary and no mitotic figures were detectable. As the concept of metastasizing leiomyoma is confusing, the accumulation of additional case reports is necessary.
一名44岁女性因多发性子宫肌瘤行子宫切除术入院。入院时胸部X线片显示右肺野有一个孤立结节。切除的包含子宫肌瘤的标本显示为高分化平滑肌瘤,无核异型性或核分裂象。肺肿瘤切除标本的组织学表现与子宫肌瘤相似,无任何核分裂迹象。类似病例已被报道为所谓的良性转移性平滑肌瘤,通常被视为低度恶性或平滑肌瘤病。然而,我们认为该病例为原发性肺平滑肌瘤合并子宫肌瘤,因为肺部病变为孤立性且未检测到核分裂象。由于转移性平滑肌瘤的概念令人困惑,因此需要积累更多病例报告。