[大鼠肾脏细胞增殖动力学及内源性抑制剂的作用]
[Dynamics of cell proliferation in rat kidney and effect of endogenous inhibitors].
作者信息
Shentseva E A, Shevtsova M Ia, Malyshev A B, Nikitin V N
出版信息
Biull Eksp Biol Med. 1993 May;115(5):523-5.
PMID:8043843
Abstract
The age dynamics of albino rat kidney cell proliferation in conditions of compensatory hypertrophy and influence of endogenous inhibitors on this process have been studied. The lack of influence of repeated injection of inhibitors on kidneys cell division of 1-month old rats has been shown, while the level of kidney proliferation of 3-month old rat and 12-month old rat decreased of about 50% and of 24-month old rat decreased of about 34%.
摘要
研究了白化大鼠在代偿性肥大条件下肾细胞增殖的年龄动态以及内源性抑制剂对这一过程的影响。结果表明，重复注射抑制剂对1月龄大鼠肾细胞分裂没有影响，而3月龄大鼠和12月龄大鼠的肾增殖水平分别下降了约50%和24月龄大鼠下降了约34%。
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