Tabrah F L, Tanner R, Vega R, Batkin S
Department of Physiology, University of Hawaii John A. Burns School of Medicine, Straub Clinic and Hospital, Inc.
Hawaii Med J. 1994 Apr;53(4):112-5, 119.
Compressed air, and more recently hyperbaric oxygen, have been used and misused in medical treatment for more than 300 years. Advances in physiology have led to rational protocols for hyperbaric oxygen use. Hyperbaric oxygen will enhance wound healing by fibroblast and capillary proliferation, suppress infection, reduce edema, reverse CNS damage from carbon monoxide and cyanide poisoning, and reduce clostridial alpha toxins. Monoplace and multiplace chambers are used for treatment during which EKG and oxygen tissue monitoring, as well as hemodynamic and respiratory support, can be continued, iatrogenic air embolism and diving decompression sickness demand immediate treatment. Investigative uses of adjunct therapy for several other clinical problems include treatment of MS, acute spinal cord injuries, and acute MI. Specific indications agreed on by the Undersea and Hyperbaric Medicine Society are recognized by most third-party payers including Medicare, Champus, and HMSA. Hyperbaric medicine remains a fertile area for basic physiologic investigation and outcomes research.
压缩空气，以及最近的高压氧，在医疗中已被使用和滥用了300多年。生理学的进展已产生了合理的高压氧使用方案。高压氧将通过成纤维细胞和毛细血管增殖促进伤口愈合，抑制感染，减轻水肿，逆转一氧化碳和氰化物中毒所致的中枢神经系统损伤，并减少梭菌α毒素。单人舱和多人舱用于治疗，在此期间可继续进行心电图和氧组织监测，以及血流动力学和呼吸支持，医源性空气栓塞和潜水减压病需要立即治疗。高压氧辅助治疗其他几种临床问题的研究用途包括治疗多发性硬化症、急性脊髓损伤和急性心肌梗死。包括医疗保险、军人家属医疗保健计划和夏威夷医疗服务协会在内的大多数第三方支付机构都认可水下和高压氧医学协会商定的具体适应症。高压氧医学仍然是基础生理学研究和结果研究的一个富有成果的领域。
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