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[评估单症状性视神经炎青少年发生多发性硬化风险的电生理方法]

[Electrophysiological methods in assessing the risk for the development of multiple sclerosis in adolescents with monosymptomatic optic neuritis].

作者信息

Guseva M R, Fil'chikova L I, Mosin I M, Kriukovskikh O N, Val'skiĭ V V

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1993;93(2):64-8.

PMID:8048310
Abstract

Pattern electroretinograms and visual evoked potentials (VEP) were investigated in response to reversal checker-board patterns with different sizes of checks in 13 adolescents with monosymptomatic optic neuritis in acute period and in the course of convalescence 1-2 and 12-36 months after the disease onset. All the children underwent computer tomography of the orbit and brain. The results allowed identification of high and low multiple sclerosis risk groups. The high risk can be proved by a progressive increase of VEP latency 1-2 months after the disease onset and its significant advance in later period of optic neuritis. Normal VEP latency in late optic neuritis shows a low degree of its development.

摘要

对13例急性期单症状性视神经炎青少年以及发病后1 - 2个月和12 - 36个月恢复期的患者,采用不同方格大小的翻转棋盘图案刺激,研究了图形视网膜电图和视觉诱发电位(VEP)。所有儿童均接受了眼眶和脑部的计算机断层扫描。结果有助于识别高、低多发性硬化风险组。疾病发作后1 - 2个月VEP潜伏期逐渐增加,以及在视神经炎后期其显著延长可证明高风险。视神经炎后期VEP潜伏期正常表明其发展程度较低。

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