姿势和年龄与尿蛋白排泄的关系。
Relationship of posture and age to urinary protein excretion.
作者信息
Mahurkar S D, Dunea G, Pillay V K, Levine H, Gandhi V
出版信息
Br Med J. 1975 Mar 29;1(5960):712-4. doi: 10.1136/bmj.1.5960.712.
The influence of posture and age on urinary protein excretion was studied in 120 normal men volunteers. The supine excretion rate was less than 140 mug/min in all but two people (median value 38 mug/min) and tended to increase with age. The excretion rate decreased on quiet standing in 80% of people, which corresponded to a fall in creatinine-clearance. In the remaining 20% protein excretion increased on standing but generally remained within normal limits and was dissociated from changes in creatinine clearances. This increase was more prevalent in younger people and may represent a phenomenon analogous to orthostatic proteinuria, differing only quantitatively.
在120名正常男性志愿者中研究了姿势和年龄对尿蛋白排泄的影响。除两人外，所有人的仰卧位排泄率均低于140微克/分钟（中位数为38微克/分钟），且排泄率有随年龄增加的趋势。80%的人静立后排泄率下降，这与肌酐清除率的降低相对应。其余20%的人站立时蛋白排泄增加，但一般仍在正常范围内，且与肌酐清除率的变化无关。这种增加在年轻人中更常见，可能代表一种类似于体位性蛋白尿的现象，只是在数量上有所不同。
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