Hellmann A
Kliniki Hematologii I.Ch.W. Akademii Medycznej w Gdańsku.
Acta Haematol Pol. 1994;25(2 Suppl 1):142-7.
Interleukin 2 (IL-2) is a cytokine which activates cytotoxic cells and stimulates T suppressor cells and may play a role in the treatment of neoplastic disorders. The majority of clinical trials were performed in renal carcinoma and melanoma. Recent studies showed that IL-2 may also play a role in the treatment of hemoproliferative disorders, but its effectiveness was shown mostly in eradication of minimal residual disease after aggressive chemotherapy and/or bone marrow transplantation.
白细胞介素2(IL-2)是一种细胞因子,可激活细胞毒性细胞并刺激抑制性T细胞,可能在肿瘤性疾病的治疗中发挥作用。大多数临床试验是在肾癌和黑色素瘤中进行的。最近的研究表明,IL-2在血液增殖性疾病的治疗中也可能起作用,但其有效性主要体现在积极化疗和/或骨髓移植后清除微小残留病方面。