N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation.

Suppr

超能文献

作者信息

Hanna P E

机构信息

Department of Medicinal Chemistry, University of Minnesota, Minneapolis 55455.

出版信息

Adv Pharmacol. 1994;27:401-30. doi: 10.1016/s1054-3589(08)61041-8.

DOI:10.1016/s1054-3589(08)61041-8

PMID:8068562

Abstract

摘要

相似文献

N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation.

Adv Pharmacol. 1994;27:401-30. doi: 10.1016/s1054-3589(08)61041-8.

Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase.近交系仓鼠组织胞质溶胶中S-乙酰辅酶A依赖性酶对致癌性N-羟基芳胺的乙酰化基因型依赖性代谢激活：与芳胺N-乙酰基转移酶的关系。

Carcinogenesis. 1987 Dec;8(12):1767-74. doi: 10.1093/carcin/8.12.1767.

Rat mammary gland carcinogenesis after local injection of N-hydroxy-N-acyl-2-aminofluorenes: relationship to metabolic activation.局部注射N-羟基-N-酰基-2-氨基芴后大鼠乳腺的致癌作用：与代谢活化的关系。

Carcinogenesis. 1982;3(3):233-40. doi: 10.1093/carcin/3.3.233.

Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.环境污染物及强诱变剂3-硝基苯并蒽酮在被人肝细胞溶质中的NAD(P)H:醌氧化还原酶还原并经乙酰转移酶和磺基转移酶结合后形成DNA加合物。

Cancer Res. 2005 Apr 1;65(7):2644-52. doi: 10.1158/0008-5472.CAN-04-3544.

In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.N-羟基-2-氨基-α-咔啉的体外生物活化作用

Carcinogenesis. 2000 Jul;21(7):1347-54.

Fatty acid biosynthesis during brain development.

Adv Exp Med Biol. 1978;101:17-26. doi: 10.1007/978-1-4615-9071-2_2.

Relationship between the rate of axoplasmic transport and subcellular distribution of enzymes involved in the synthesis of norepinephrine.去甲肾上腺素合成过程中相关酶的轴浆运输速率与亚细胞分布之间的关系。

J Neurochem. 1973 Jun;20(6):1691-706. doi: 10.1111/j.1471-4159.1973.tb00285.x.

Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.马兜铃酸I和II与NADPH：醌氧化还原酶、磺基转移酶和N-乙酰转移酶激活作用的比较。

Neuro Endocrinol Lett. 2011;32 Suppl 1:57-70.

Purification, properties and function of N-hydroxyarylamine O-acetyltransferase.

Adv Exp Med Biol. 1986;197:551-61. doi: 10.1007/978-1-4684-5134-4_52.

The effects of ascorbic acid deficiency and repletion on pulmonary, renal, and hepatic drug metabolism in the guinea pig.

Arch Biochem Biophys. 1977 Mar;179(2):663-71. doi: 10.1016/0003-9861(77)90155-2.

引用本文的文献

Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.中国人群中N-乙酰转移酶2基因与表型和膀胱癌风险的差异关联。

Oncotarget. 2016 Jun 28;7(26):40012-40024. doi: 10.18632/oncotarget.9475.

Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery.芳香胺 N-乙酰基转移酶：从药物代谢和药物遗传学到药物发现。

Br J Pharmacol. 2014 Jun;171(11):2705-25. doi: 10.1111/bph.12598.

Arylamine N-acetyltransferases: a structural perspective.芳香胺 N-乙酰基转移酶：结构视角。

Br J Pharmacol. 2013 Jun;169(4):748-60. doi: 10.1111/bph.12182.

What differs on the enzymatic acetylation mechanisms for arylamines and arylhydrazines substrates? A theoretical study.芳胺和芳基肼底物的酶促乙酰化机制有何不同？一项理论研究。

Res Lett Biochem. 2009;2009:783035. doi: 10.1155/2009/783035. Epub 2009 Aug 6.

Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190.通过定点突变近侧保守残基 Tyr190 探究仓鼠芳香胺 N-乙酰转移酶 2 催化三联体的催化潜力。

FEBS J. 2009 Dec;276(23):6928-41. doi: 10.1111/j.1742-4658.2009.07389.x. Epub 2009 Oct 23.

Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.对比海洋分枝杆菌和结核分枝杆菌的芳香胺 N-乙酰转移酶。

Protein J. 2009 Aug;28(6):281-93. doi: 10.1007/s10930-009-9193-0.

Quantitative tissue and gene-specific differences and developmental changes in Nat1, Nat2, and Nat3 mRNA expression in the rat.大鼠中Nat1、Nat2和Nat3 mRNA表达的定量组织和基因特异性差异以及发育变化。

Drug Metab Dispos. 2008 Dec;36(12):2445-51. doi: 10.1124/dmd.108.023564. Epub 2008 Sep 17.

Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.人类N-乙酰转移酶2单核苷酸多态性的结构/功能评估

Curr Drug Metab. 2008 Jul;9(6):471-86. doi: 10.2174/138920008784892065.

Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa.铜绿假单胞菌芳胺N-乙酰基转移酶的动力学特性分析

BMC Biochem. 2007 Mar 20;8:3. doi: 10.1186/1471-2091-8-3.

Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.重组人芳胺N-乙酰基转移酶1的过表达、纯化及特性分析

Protein J. 2005 Feb;24(2):65-77. doi: 10.1007/s10930-004-1513-9.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验