Mayer G, Bousquet J, Vanhems E, Dubuisson L
C R Acad Hebd Seances Acad Sci D. 1975 Jun 30;280(25):2877-80.
The seminiferous tubulars of rats testis, subject to the action of Misulban during their foetal life, contain only Sertoli cells and constitute a good model for their study. From the ultrastructural point of view, these cells present several important mitochondria of tubular crest from, an abundant smooth endoplasmic reticulum, a Golgi apparatus well developed, a cytoplasm rich in ribosomes, Lipids droplets and intercellular junctions whose number increases with age. The administration of diethylstilbestrol, which inhibits gonadotropic and androgenic secretions reduces the signs of activity in the Sertoli cells.
在胎儿期受米苏尔班作用的大鼠睾丸曲细精管仅含有支持细胞,是研究支持细胞的良好模型。从超微结构角度看,这些细胞有若干重要的嵴状线粒体、丰富的滑面内质网、发育良好的高尔基体、富含核糖体、脂滴的细胞质以及数量随年龄增加的细胞间连接。抑制促性腺和雄激素分泌的己烯雌酚的给药会降低支持细胞的活性迹象。