Landi A, Morgagni P, Folli S, Dell'Amore D
Divisione di Chirurgia Generale e Toracica, Ospedale G.B. Morgagni, L. Pierantoni, U.S.L. n. 38, Forlì.
G Chir. 1994 Apr;15(4):167-70.
Postoperative morbidity and mortality were correlated with the preoperative results of three widely used pulmonary function tests (FVC, FEV1, FEV1/FVC) in 100 consecutive patients who underwent pneumonectomy for lung carcinoma. Factor analyzed following operation included thirty-day mortality, incidence of cardiovascular and respiratory complications, number of individuals requiring prolonged mechanical ventilation. Nineteen patients had a forced vital capacity (FVC) of 70% or less of the normal value, seven had a one-second forced expiratory volume (FEV1) of 1.5 liters or less, and thirty-three had a FEV1 of less than 2 liters. Fourteen patients had a FEV1/FVC ratio of 65% or less. There were no differences in morbidity or mortality between these patients and those presenting higher test scores. As a general rule, decisions regarding operability and extent of resection cannot be made solely on the basis of the three spirometry tests reviewed.
在连续100例因肺癌接受肺切除术的患者中,术后发病率和死亡率与三项广泛使用的肺功能测试(用力肺活量(FVC)、第一秒用力呼气容积(FEV1)、FEV1/FVC)的术前结果相关。术后分析的因素包括30天死亡率、心血管和呼吸系统并发症的发生率、需要长时间机械通气的人数。19例患者的用力肺活量(FVC)为正常值的70%或更低,7例患者的第一秒用力呼气容积(FEV1)为1.5升或更低,33例患者的FEV1小于2升。14例患者的FEV1/FVC比值为65%或更低。这些患者与测试分数较高的患者在发病率或死亡率方面没有差异。一般来说,不能仅根据所审查的三项肺量计测试来做出关于可手术性和切除范围的决定。