Suppr超能文献

慢性阻塞性肺疾病患者的营养支持

Nutritional support for the patient with chronic obstructive pulmonary disease.

作者信息

Pezza M, Iermano C, Tufano R

机构信息

Institute of Anesthesiology and Intensive Care, University of Naples Federico II Medical School, Italy.

出版信息

Monaldi Arch Chest Dis. 1994 Jun;49(3 Suppl 1):33-9.

PMID:8087136
Abstract

Malnutrition is reported in a significant percentage of COPD patients, and it may contribute to the onset of acute respiratory failure. Weight loss is due to the decrease of caloric support caused by breathlessness, digestive alterations due to hypoxemia and to the increase of energy expenditures caused by increased baseline requirements and diet induced thermogenesis (DIT). Malnutrition limits the ability to produce surfactant, leads to reduced protein synthesis, reduces cell mediated immune responses raising the patient's susceptibility to lung infection and affects the functioning of peripheral and respiratory muscles. The combination of malnutrition and COPD has devastating effects. Nutritional support is, therefore, an important part of therapy for the stable COPD outpatients, for hospital COPD patients and for ICU COPD patients. The nutritional program should follow an assessment of the nutritional status. With a correct number of calories and a correct composition of nutrients, it is possible to help these patients in the different clinical stages of the disease.

摘要

据报道,相当比例的慢性阻塞性肺疾病(COPD)患者存在营养不良,这可能会导致急性呼吸衰竭的发生。体重减轻是由于呼吸困难导致热量摄入减少、低氧血症引起消化功能改变以及基础需求增加和饮食诱导产热(DIT)导致能量消耗增加。营养不良会限制表面活性剂的产生能力,导致蛋白质合成减少,降低细胞介导的免疫反应,增加患者肺部感染的易感性,并影响外周和呼吸肌的功能。营养不良与COPD共同作用具有毁灭性影响。因此,营养支持是稳定期COPD门诊患者、住院COPD患者以及ICU中COPD患者治疗的重要组成部分。营养方案应在评估营养状况之后制定。通过提供正确数量的卡路里和正确的营养成分组合,有助于这些处于疾病不同临床阶段的患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验