Lee K L, Buckley H R, Campbell C C
Sabouraudia. 1975 Jul;13(2):148-53. doi: 10.1080/00362177585190271.
A chemically defined medium composed of 6 amino acids, biotin, inorganic salts and glucose for the growth of yeast and mycelial phases of Candida albicans at 25 degrees C and 37 degrees of C respectively was developed based on the aminopeptidase(s) profile of the fungus. This medium has proved successful in maintaining the growth characteristics of both phases during serial transfers. The relative pathogenicity, virulence, invasiveness and immunogenicity of the yeast and mycelial phases are discussed.
基于白色念珠菌的氨肽酶谱,开发了一种化学限定培养基,该培养基由6种氨基酸、生物素、无机盐和葡萄糖组成,分别用于白色念珠菌在25℃和37℃下酵母期和菌丝期的生长。事实证明,这种培养基在连续传代过程中能够成功维持两个阶段的生长特性。文中还讨论了酵母期和菌丝期的相对致病性、毒力、侵袭性和免疫原性。