小鼠赖氨酰氧化酶基因（Lox）位于第18号染色体上。
The mouse lysyl oxidase gene (Lox) resides on chromosome 18.
作者信息
Chang Y S, Svinarich D M, Yang T P, Krawetz S A
机构信息
Center for Molecular Biology, Wayne State University, Detroit, MI.
出版信息
Cytogenet Cell Genet. 1993;63(1):47-9. doi: 10.1159/000133500.
Lysyl oxidase initiates crosslink formation of the connective tissue matrix. This enzyme can also revert the ras phenotype in mouse NIH 3T3-transformed cells. Even though lysyl oxidase may participate in many different biological processes, its chromosomal assignment in the mouse genome remains to be addressed. Southern analysis of a panel of Chinese hamster x mouse somatic cell hybrids was utilized to assign the lysyl oxidase gene (Lox) to mouse Chromosome 18.
赖氨酰氧化酶启动结缔组织基质的交联形成。这种酶还可以使小鼠NIH 3T3转化细胞中的ras表型恢复正常。尽管赖氨酰氧化酶可能参与许多不同的生物学过程，但其在小鼠基因组中的染色体定位仍有待确定。利用一组中国仓鼠与小鼠体细胞杂种进行Southern分析，将赖氨酰氧化酶基因（Lox）定位于小鼠第18号染色体。
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