新生儿病房护理操作、其他局部特征与肠道细菌传播之间的关系。

Relation between nursing procedures, other local characteristics and transmission of enteric bacteria in neonatal wards.

作者信息

Fryklund B, Tullus K, Burman L G

机构信息

Department of Bacteriology, National Bacteriological Laboratory, Stockholm, Sweden.

出版信息

J Hosp Infect. 1993 Mar;23(3):199-210. doi: 10.1016/0195-6701(93)90025-u.

DOI:10.1016/0195-6701(93)90025-u

PMID:8099094

Abstract

Faecal colonization patterns were studied in 22 neonatal special care units (N = 953 babies) using a novel method for typing of Escherichia coli, Klebsiella spp. and Enterobacter spp. isolates. Sporadic strains of E. coli (found in only one infant in a ward) were taken to indicate natural colonization, whereas local spread of E. coli strains or colonization with sporadic or spreading strains of Klebsiella spp. and Enterobacter spp. was regarded as abnormal (non-maternal) colonization. All apparent risk factors for abnormal neonatal colonization with enteric bacteria identified were modifiable (ward size, staff work load, antibiotic policy, hygienic precautions). Another encouraging finding was that variables harder to modify (crowding, intensity of care) appeared to be unimportant in influencing neonatal colonization patterns with such bacteria.

摘要

采用一种新型方法对大肠杆菌、克雷伯菌属和肠杆菌属分离株进行分型，在22个新生儿重症监护病房（共953名婴儿）中研究了粪便定植模式。病房中仅在一名婴儿身上发现的散发性大肠杆菌菌株被视为自然定植，而大肠杆菌菌株的局部传播或克雷伯菌属和肠杆菌属散发性或传播性菌株的定植则被视为异常（非母体）定植。已确定的所有导致新生儿肠道细菌异常定植的明显风险因素都是可改变的（病房大小、工作人员工作量、抗生素政策、卫生预防措施）。另一个令人鼓舞的发现是，较难改变的因素（拥挤程度、护理强度）在影响此类细菌的新生儿定植模式方面似乎并不重要。