维生素E治疗迟发性运动障碍
Vitamin E treatment of tardive dyskinesia.
作者信息
Adler L A, Peselow E, Rotrosen J, Duncan E, Lee M, Rosenthal M, Angrist B
机构信息
Psychiatry Service, New York Department of Veterans Affairs Medical Center, NY 10010.
出版信息
Am J Psychiatry. 1993 Sep;150(9):1405-7. doi: 10.1176/ajp.150.9.1405.
OBJECTIVE
The authors studied the effects of vitamin E treatment of tardive dyskinesia; earlier studies have produced contradictory results.
METHOD
Twenty-eight patients with tardive dyskinesia were treated in a double-blind, parallel-group comparison study of 8-12 weeks of treatment with vitamin E (1600 IU/day) or matching placebo capsules.
RESULTS
The Abnormal Involuntary Movement Scale scores of the patients treated with vitamin E improved significantly compared to the scores of the patients given placebo.
CONCLUSIONS
These results support earlier findings of the efficacy of vitamin E in treating tardive dyskinesia.
目的
作者研究了维生素E治疗迟发性运动障碍的效果；早期研究结果相互矛盾。
方法
对28例迟发性运动障碍患者进行了一项双盲、平行组对照研究，患者接受为期8 - 12周的维生素E（1600国际单位/天）治疗或匹配的安慰剂胶囊治疗。
结果
与服用安慰剂的患者相比，接受维生素E治疗的患者异常不自主运动量表评分有显著改善。
结论
这些结果支持了早期关于维生素E治疗迟发性运动障碍有效性的研究发现。
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