Daly M D
Department of Physiology, Royal Free Hospital School of Medicine, London, U.K.
Adv Exp Med Biol. 1993;337:333-43. doi: 10.1007/978-1-4615-2966-8_47.
The differential nature of the modulation of excitatory inputs from various cardiovascular receptor groups by pulmonary stretch afferents, driven by lung inflation, and the central inspiratory neuronal activity, has been demonstrated. At levels of activity of pulmonary stretch afferents and of central inspiratory drive that almost completely suppress the bradycardia of stimulation of the carotid bodies, the response to stimulation of the arterial baroreceptors and cardiac C fibre endings was reduced by 30-58%. In contrast, the bradycardia evoked by pulmonary C fibre stimulation was not significantly affected by either respiratory mechanism.
由肺扩张驱动的肺牵张传入神经对来自各种心血管受体组的兴奋性输入的调节以及中枢吸气神经元活动的差异性质已得到证实。在肺牵张传入神经活动和中枢吸气驱动水平几乎完全抑制颈动脉体刺激引起的心动过缓时，对动脉压力感受器和心脏C纤维末梢刺激的反应降低了30% - 58%。相比之下，肺C纤维刺激诱发的心动过缓不受任何一种呼吸机制的显著影响。
