Laville J M, Lakermance P, Limouzy F
Service de Chirurgie Infantile, C.H.D. Félix Guyon, Ile de la Réunion.
J Pediatr Orthop. 1994 Jan-Feb;14(1):63-73. doi: 10.1097/01241398-199401000-00014.
Thirty-eight cases of Larsen's syndrome in patients living on Reunion Island were analyzed, with an average follow-up of 13 years. Fourteen of these patients died of early complications secondary to dislocation of the cervical spine, tracheomalacias, heart disease, and severe respiratory infection. These children pose a problem of planning early treatment. Clubfeet must be treated conservatively early, and operation should be postponed until after knee deformities are corrected by plaster cast and/or early operation. Unilateral hip dislocations should be treated surgically in the second year of life. Treatment of bilateral hip dislocations is best neglected. Finally, the spinal status of these children must be monitored throughout their life.
对留尼汪岛38例拉森综合征患者进行了分析，平均随访13年。其中14例患者死于颈椎脱位、气管软化、心脏病和严重呼吸道感染等早期并发症。这些儿童带来了早期治疗规划的问题。马蹄内翻足必须尽早进行保守治疗，手术应推迟到通过石膏固定和/或早期手术矫正膝关节畸形之后。单侧髋关节脱位应在患儿1岁时进行手术治疗。双侧髋关节脱位最好不予治疗。最后，必须对这些儿童的脊柱状况进行终身监测。
