Lehman A F, Myers C P, Corty E, Thompson J
Department of Psychiatry, University of Maryland School of Medicine, Baltimore 21201.
J Nerv Ment Dis. 1994 Mar;182(3):164-7. doi: 10.1097/00005053-199403000-00006.
This study compares the severity of DSM-III-R psychoactive substance use disorders (PSUDs) among dually diagnosed psychiatric inpatients with independent axis I mental disorders (IMDs) with the severity of PSUDs among: a) patients from the same hospitals with PSUD-related organic mental syndromes (PSUD-OMD) and b) patients from a residential drug-treatment program with PSUDs but no axis I mental disorders. The drug-use disorders among the group 1 (IMD+PSUD) patients were less severe on multiple indicators from the Structured Clinical Interview for DSM-III-R (SCID) and the Addiction Severity Index compared with the drug-use disorders among the other two groups. This did not hold for alcohol disorders. These findings carry potential implications for treatment strategies for the mentally ill with drug use.
本研究比较了患有独立的轴I精神障碍(IMD)的双重诊断精神科住院患者中DSM-III-R精神活性物质使用障碍(PSUD)的严重程度与以下两类患者中PSUD的严重程度:a)来自同一家医院患有与PSUD相关的器质性精神综合征(PSUD-OMD)的患者,以及b)来自住院药物治疗项目、患有PSUD但无轴I精神障碍的患者。与其他两组患者的药物使用障碍相比,第1组(IMD+PSUD)患者的药物使用障碍在来自《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)的结构化临床访谈(SCID)和成瘾严重程度指数的多个指标上不太严重。酒精障碍方面并非如此。这些发现对患有药物使用问题的精神病患者的治疗策略具有潜在意义。