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[布隆迪南伊姆博地区尼安扎湖社区一个稳定的高度流行疟疾地区的青年死亡率和发病率]

[Mortality and morbidity at young ages in a stable hyperendemic malaria region, community Nyanza-Lac, Imbo South, Burundi].

作者信息

Delacollette C, Barutwanayo M

出版信息

Bull Soc Pathol Exot. 1993;86(5):373-9.

PMID:8124110
Abstract

A malaria control programme based on the extensive use of impregnated bednets is planned in an stable hyperendemic malaria area in Burundi (Nyanza-Lac district) where the average number of infective bites per person per year was 312 during the preintervention period. In order to be able to evaluate in depth this important intervention, vital events such as mortality and morbidity were studied in under five-year-old-children during a full year period between June 1990 and May 1991 before the intervention. Village reporters have visited every three weeks 1,200 randomly selected households and completed specific mortality and morbidity questionnaires (prevalence and incidence with a 7 day recall period) adapted from "MRC" questionnaires in the Gambia. Infant and child mortality rates were respectively 108 and 24/1000/y. The definition of a malaria death was based on the opinion of 2 physicians (by consensus) and on the following symptoms alone or in combination: fever < 8 days, convulsions or unconsciousness in the absence of symptoms suggesting an alternative diagnosis. According to this previous definition, malaria was responsible for more than 30% of mortality in under five-year-old-children (specific mortality rate 0-4 year: 14.4/1000/y; specific rate 0-1 year: 38/1000/y; specific rate 1-4 year: 8/1000/y). Diarrhoea (8.1/1000/y) and respiratory tract infections (6.0/1000/y) were respectively the second and third major causes of death. Malaria was also the first cause of morbidity with a yearly average incidence rate of 1.17/person in children under 5 years. Malaria morbidity incidence was highest in children aged 1-2 years (1.79 malaria episodes/person/y).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在布隆迪一个稳定的高度疟疾流行区(尼扬扎 - 拉克区)计划开展一项基于广泛使用浸药蚊帐的疟疾控制项目,在干预前时期,该地区每人每年平均感染性叮咬次数为312次。为了能够深入评估这一重要干预措施,在1990年6月至1991年5月干预前的一整年时间里,对五岁以下儿童的死亡和发病等重要事件进行了研究。乡村报告员每三周走访1200户随机选取的家庭,并填写根据冈比亚“MRC”问卷改编的特定死亡和发病调查问卷(患病率和发病率,回忆期为7天)。婴儿和儿童死亡率分别为108‰和24‰/年。疟疾死亡的定义基于两名医生(经共识)的意见,且仅依据以下单独或组合出现的症状:发热<8天、抽搐或无意识,且无提示其他诊断的症状。根据此前定义,疟疾导致五岁以下儿童死亡率超过30%(0 - 4岁特定死亡率:14.4‰/年;0 - 1岁特定死亡率:38‰/年;1 - 4岁特定死亡率:8‰/年)。腹泻(8.1‰/年)和呼吸道感染(6.0‰/年)分别是第二和第三大主要死因。疟疾也是发病的首要原因,五岁以下儿童年平均发病率为1.17/人。疟疾发病率在1 - 2岁儿童中最高(1.79次疟疾发作/人/年)。(摘要截取自250字)

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