Cholestasis in infancy: 1.

Although conjugated hyperbilirubinaemia is not common in infants its presence carries serious implications in the majority of cases. It is therefore important that those responsible for the care of sick infants have a good understanding of the causes of cholestasis in infancy. Early diagnosis facilitates early treatment which is the key to optimal management in many such children. In the first of two articles, the major causes of cholestasis in infancy are discussed.