干扰素的使用可调节热应激对家禽生产的负面影响。

The use of interferon modulates the negative effects of heat stress on poultry production.

作者信息

Fulton R W, Teeter R G, Cummins J M, Georgiades J A, Hutcheson D P

机构信息

Department of Veterinary Parasitology, Oklahoma State University, College of Veterinary Medicine, Stillwater 74078.

出版信息

Arch Immunol Ther Exp (Warsz). 1993;41(3-4):209-12.

PMID:8129564

Abstract

A trial was conducted with broilers reared in two temperature environments; one was thermoneutral and the other had cycling ambient temperatures. Human interferon alpha (HuIFN-alpha) was added to the drinking water daily at four dose levels (0.0, 0.01, 0.1 and 1.0 international units (IU) per ml of drinking water). The trial began with 21 day old chicks housed either in a thermoneutral (24 degrees C) or a cycling ambient temperature (24-36 degrees C) environment. Interferon added to water at the highest concentration (1.0 IU/ml) improved surviability of birds in the cycling ambient temperature (24-36 degrees C) environment (P < 0.05). Birds housed in the cycling (24-36 degrees C) environment, drinking the lowest concentration of IFN-alpha 0.01 IU/ml, had a significantly improved weight gain-to-feed ratio. Oral IFN-alpha reduced the cost of production for birds reared in a cycling ambient temperature environment.

摘要

对在两种温度环境中饲养的肉鸡进行了一项试验；一种是热中性环境，另一种是环境温度循环变化的环境。每天以四种剂量水平（每毫升饮用水0.0、0.01、0.1和1.0国际单位（IU））将人干扰素α（HuIFN-α）添加到饮用水中。试验从21日龄的雏鸡开始，将它们饲养在热中性（24℃）或环境温度循环变化（24 - 36℃）的环境中。添加到水中的最高浓度（1.0 IU/ml）的干扰素提高了处于环境温度循环变化（24 - 36℃）环境中的鸡的存活率（P < 0.05）。饲养在环境温度循环变化（24 - 36℃）环境中、饮用最低浓度（0.01 IU/ml）干扰素α的鸡，其增重与饲料比显著提高。口服干扰素α降低了在环境温度循环变化环境中饲养的鸡的生产成本。