Weinstein M, Wood J, Greenfield D D
Department of Demography, Georgetown University, Washington, D.C. 20057.
Soc Biol. 1993 Spring-Summer;40(1-2):106-30. doi: 10.1080/19485565.1993.9988839.
Unmeasured variation has long been a concern in analyses of the waiting time to conception. Recent work by Heckman and Walker (1991) and Trussell and Rodriguez (1990) has underscored the fact that statistical considerations alone cannot discriminate among likely models describing the distribution. Here, we specify a single theoretically important source of heterogeneity, namely variability in intrauterine mortality, and assess its effects on the waiting times to a conception which results in a live birth. We find that the effects on the waiting times to a conception which results in a live birth. We find that the effects of variation in fetal loss are confined to the tail of the distribution. Unless variation in fetal loss is extremely large or a substantial proportion of observed waiting times are initiated at late ages, variation in fetal loss does not appear to explain much variation in conception waits. We conclude that heterogeneity in fetal loss does not explain the variation in fecundability that has been observed for first birth intervals. This conclusion supports the hypothesis that at early ages (below age 35) variation in the waiting time to a fertile conception may largely reflect the proportion of nonsusceptible couples in the population. The analyses suggest that for the purposes of testing theoretically motivated models, future efforts should be directed toward examining reproductive experience after age 35 and toward incorporating information on characteristics of the fertile period as it becomes known.
在对受孕等待时间的分析中,未测量的变异一直是个令人担忧的问题。赫克曼和沃克(1991年)以及特鲁塞尔和罗德里格斯(1990年)最近的研究强调了这样一个事实,即仅靠统计考量无法区分描述分布的可能模型。在此,我们明确了一个理论上重要的异质性来源,即子宫内死亡率的变异性,并评估其对导致活产的受孕等待时间的影响。我们发现其对导致活产的受孕等待时间有影响。我们发现胎儿丢失变异的影响仅限于分布的尾部。除非胎儿丢失的变异极大,或者观察到的等待时间中有很大比例是在高龄时开始的,否则胎儿丢失的变异似乎无法解释受孕等待时间的大量变异。我们得出结论,胎儿丢失的异质性并不能解释初育间隔中观察到的生育力变异。这一结论支持了这样一种假设,即在早期年龄(35岁以下),受孕等待时间的变异可能在很大程度上反映了人群中不易受孕夫妇的比例。分析表明,为了检验理论驱动的模型,未来的研究应致力于研究35岁以后的生殖经历,并在已知生育期特征时纳入相关信息。