白色念珠菌芽管在体外试验中对小鼠组织的黏附情况。

Adherence of Candida albicans germ tubes to murine tissues in an ex vivo assay.

作者信息

López-Ribot J L, Vespa M N, Chaffin W L

机构信息

Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock 79430.

出版信息

Can J Microbiol. 1994 Jan;40(1):77-81. doi: 10.1139/m94-013.

DOI:10.1139/m94-013

PMID:8149312

Abstract

Adhesion of Candida albicans germ tubes to murine tissues was examined. An ex vivo assay previously employed to examine adhesion of yeast cells of C. albicans was adapted for use with germ tubes. Binding of germ tubes to kidney, liver, spleen, and lymph node tissues was found to occur throughout the tissue section, with little morphologic specificity. In general, more organisms adhered to spleen and lymph node tissues than to kidney and liver tissues. Observation of adhesion with scanning organisms adhered to spleen and lymph node tissues than to kidney and liver tissues. Observation of adhesion with scanning electron microscopy showed three germ tube-tissue interactions described as loose, tight, or embedded.

摘要

对白色念珠菌芽管与小鼠组织的黏附情况进行了检测。一种先前用于检测白色念珠菌酵母细胞黏附的体外试验方法被改编用于芽管。发现芽管与肾脏、肝脏、脾脏和淋巴结组织的结合在整个组织切片中都有发生，几乎没有形态学特异性。一般来说，黏附到脾脏和淋巴结组织的微生物比黏附到肾脏和肝脏组织的更多。用扫描电子显微镜观察黏附情况显示出三种芽管 - 组织相互作用，分别描述为松散型、紧密型或嵌入型。