Lüderitz B, Steinbeck G
MMW Munch Med Wochenschr. 1976 Mar 19;118(12):377-82.
The clinical relevance of the Wolff-Parkinson-White syndrome is determined by the occurrence of cardiac arrhythmias due to the syndrome. Occurrence and severity of the cardiac arrhythmias are mainly dependant on the electrophysiological properties of the accessory atrioventricular bypass or the refractory period of the regular and irregular pathways respectively. Programmed electrical stimulation allows the study of these properties directly in man. The treatment in patients with WPW syndrome suffering from re-entry tachyarrhythmias should be directed to an interruption of the tachycardia circuit. During sinus rhythm a suppression of spontaneously occurring ectopic beats which may initiate a tachycardia is indicated.
预激综合征的临床相关性取决于该综合征所致心律失常的发生情况。心律失常的发生及严重程度主要分别取决于房室旁道的电生理特性或正常及异常传导通路的不应期。程控电刺激可直接在人体研究这些特性。对于患有折返性快速心律失常的预激综合征患者，治疗应针对中断心动过速环路。在窦性心律时，应抑制可能引发心动过速的自发异位搏动。
