Hughes G B, Moscicki R, Barna B P, San Martin J E
Department of Otolaryngology and Communicative Disorders, Cleveland Clinic Foundation, Ohio.
Am J Otol. 1994 Mar;15(2):198-202.
Immune inner ear disease is a relatively new and distinct clinical entity that produces unexplained, rapidly progressive, bilateral sensorineural hearing loss. The diagnosis is based on clinical manifestations, positive immune laboratory testing, and beneficial response to a trial of corticosteroids. Immune laboratory tests are used to confirm a presumptive clinical diagnosis. The two tests most commonly used are the lymphocyte transformation test and Western blot immune assay. The rationale behind these tests is presented, and the role they play in laboratory diagnosis of immune inner ear disease is discussed.
免疫性内耳疾病是一种相对较新的独特临床实体，可导致不明原因的、快速进展的双侧感音神经性听力损失。诊断基于临床表现、免疫实验室检查阳性以及对皮质类固醇试验的有益反应。免疫实验室检查用于确诊初步临床诊断。最常用的两项检查是淋巴细胞转化试验和免疫印迹分析。本文阐述了这些检查背后的原理，并讨论了它们在免疫性内耳疾病实验室诊断中的作用。
