Frates M C, Benson C B, Doubilet P M, Di Salvo D N, Brown D L, Laing F C, Rein M S, Osathanondh R
Department of Radiology, Harvard Medical School, Boston, MA 02115.
Radiology. 1994 Jun;191(3):773-5. doi: 10.1148/radiology.191.3.8184062.
To review experience with early sonographic diagnosis and fertility-preserving treatment of cervical ectopic pregnancy.
The authors evaluated 12 consecutive cases of cervical ectopic pregnancy diagnosed with ultrasound (US) and treated with methods that successfully preserved the uterus. Gestational age, sonographic findings, means of conception, and method of treatment were recorded.
Gestational age at diagnosis ranged from 5.0 to 7.9 weeks. Cardiac activity was documented in nine cases. Patients were treated as follows: transvaginal US-guided injection of potassium chloride into the embryo or gestational sac (n = 6), uterine artery embolization followed by dilation and evacuation (n = 4), dilation and evacuation after ligation of uterine artery branches (n = 1), and uterine artery embolization followed by administration of systemic methotrexate (n = 1). The cervical pregnancy was successfully ablated with one treatment in all cases. No patient required hysterectomy, and only one patient required transfusion. Two patients subsequently delivered healthy babies; three other patients have been able to conceive successfully.
When cervical ectopic pregnancy is diagnosed early, US-guided termination or other conservative procedures allow preservation of the uterus, thus maintaining potential fertility.
回顾宫颈异位妊娠的早期超声诊断及保留生育功能治疗的经验。
作者评估了连续12例经超声诊断为宫颈异位妊娠并采用成功保留子宫方法治疗的病例。记录了孕周、超声检查结果、受孕方式及治疗方法。
诊断时的孕周为5.0至7.9周。9例记录有胎心搏动。患者治疗情况如下:经阴道超声引导下向胚胎或妊娠囊内注射氯化钾(6例)、子宫动脉栓塞后刮宫(4例)、子宫动脉分支结扎后刮宫(1例)、子宫动脉栓塞后全身应用甲氨蝶呤(1例)。所有病例均经一次治疗成功消除宫颈妊娠。无患者需要行子宫切除术,仅1例患者需要输血。2例患者随后分娩出健康婴儿;另外3例患者成功受孕。
当宫颈异位妊娠早期被诊断时,超声引导下终止妊娠或其他保守治疗方法可保留子宫,从而维持潜在生育能力。