Miyoshi Y, Suemune S, Yoshida A, Takemura M, Nagase Y, Shigenaga Y
Department of Oral Anatomy, Hiroshima University School of Dentistry, Japan.
J Comp Neurol. 1994 Feb 8;340(2):207-32. doi: 10.1002/cne.903400207.
Previous studies indicate that vibrissa, nonvibrissa, guard hair, hairy skin, and periodontal ligament afferents give rise to morphologically distinct terminal arbors in the trigeminal nuclei principalis (Vp) and oralis (Vo) in the cat. The present study describes the extent to which morphological and functional relationships exist in the nuclei interpolaris (Vi) and caudalis (Vc). Twenty-two fibers were physiologically characterized and stained by intra-axonal HRP injection techniques. The fast adapting (FA) vibrissa (VF) afferents gave rise to compact and circumscribed arbors in Vi and Vc. These tended to be larger in Vc than in Vi. The slowly adapting (SA) vibrissa (VS) afferents in Vi and Vc had more widespread and larger arbors than those of the VF afferents. The VS arbors in Vc tended to be larger and less circular than those in Vi. Guard hair (GH) afferents gave rise to circumscribed arbors in both nuclei, but those in Vc tended to have larger and more circular arbors than those in Vi. Down hair (DH) afferents gave rise to small, circumscribed arbors or a few distinct patches of boutons within a small area in Vi; arbors in Vc were less extensive and "stringy." Unlike other afferents, DH arbors were larger in Vi than in Vc, but smaller than those of GH afferents in either nuclei. The SA hairy skin (SS) afferents had arbors that were widespread with a few distinct patches of boutons; the arbors in Vc were larger than those in Vi. The arbors of SS afferents were smaller than those of VS and GH afferents in both nuclei. Like GH afferents, FA periodontal ligament (PF) afferents gave rise to large and circumscribed arbors in Vi, although the arbors in Vc were smaller and less dense. The present study demonstrated significant functional and morphological relationships for primary afferents in Vi and Vc, thus suggesting that sensory information from each of the distinct fiber or functional classes is processed in a characteristic manner in the individual nuclei.
先前的研究表明，触须、非触须、刚毛、多毛皮肤和牙周膜传入纤维在猫的三叉神经脑桥核（Vp）和三叉神经中脑核（Vo）中形成形态上不同的终末分支。本研究描述了在三叉神经脊束核吻侧亚核（Vi）和尾侧亚核（Vc）中形态与功能关系的程度。通过轴突内辣根过氧化物酶注射技术对22条纤维进行了生理特性鉴定和染色。快速适应（FA）触须（VF）传入纤维在Vi和Vc中形成紧密且界限分明的分支。这些分支在Vc中往往比在Vi中更大。Vi和Vc中的慢速适应（SA）触须（VS）传入纤维比VF传入纤维具有更广泛且更大的分支。Vc中的VS分支往往比Vi中的更大且更不呈圆形。刚毛（GH）传入纤维在两个核中均形成界限分明的分支，但Vc中的分支往往比Vi中的更大且更呈圆形。绒毛（DH）传入纤维在Vi中形成小的、界限分明的分支或在小区域内有一些离散的终扣斑；Vc中的分支范围较小且呈“丝状”。与其他传入纤维不同，DH分支在Vi中比在Vc中更大，但比任一核中的GH传入纤维分支小。慢速适应多毛皮肤（SS）传入纤维的分支广泛，有一些离散的终扣斑；Vc中的分支比Vi中的更大。SS传入纤维的分支在两个核中均比VS和GH传入纤维的分支小。与GH传入纤维一样，快速适应牙周膜（PF）传入纤维在Vi中形成大的、界限分明的分支，尽管Vc中的分支较小且密度较低。本研究证明了Vi和Vc中初级传入纤维存在显著的功能和形态关系，因此表明来自每个不同纤维或功能类别的感觉信息在各个核中以特征性方式进行处理。
