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[儿童视交叉神经胶质瘤术前及术后的眼科症状]

[The ophthalmological symptoms of chiasmatic gliomas in children in the pre- and postoperative periods].

作者信息

Serova N K, Sokolova O N, Vladimirova N A

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1994 Apr-Jun(2):20-2.

PMID:8209588
Abstract

The paper outlines the ophthalmological symptomatology in 61 children aged 2.5 to 15 years who had great and giant chiasmal gliomas. The ophthalmological symptomatology among the first clinical manifestations was found in 86.9% of cases and remained prevalent throughout the follow-up. There was a correlation between the status of visual functions and the site of a tumor. The tumor affected mainly the chiasma in 6.6% of cases, the chiasma and the both optic nerves in 26.2%, the chiasma and an optic nerve in 62.2%. The ophthalmological and neurological symptomatologies are of value in choosing a surgical treatment. A subtotal and partial removal of the tumor was performed in 51 and 10 patients, respectively. Its removal resulted in an improvement and stabilization of visual functions in 14.3 and 41.1% of cases, respectively. Thirty-three patients were followed up for 4 months to 8 years. Visual improvement occurred in 36.4% in the late period. There was a relapse in 9.1% of cases.

摘要

该论文概述了61例年龄在2.5至15岁之间患有大型和巨大型视交叉神经胶质瘤儿童的眼科症状。在86.9%的病例中,眼科症状出现在最初的临床表现中,并且在整个随访过程中一直普遍存在。视觉功能状态与肿瘤部位之间存在相关性。肿瘤主要累及视交叉的病例占6.6%,累及视交叉和双侧视神经的占26.2%,累及视交叉和一侧视神经的占62.2%。眼科和神经科症状在选择手术治疗方面具有重要意义。分别对51例和10例患者进行了肿瘤次全切除和部分切除。肿瘤切除后,分别有14.3%和41.1%的病例视觉功能得到改善和稳定。33例患者接受了4个月至8年的随访。晚期有36.4%的患者视觉功能得到改善。9.1%的病例出现复发。

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