Bauerfeind A
MMW Munch Med Wochenschr. 1976 Jul 2;118(27):871-4.
In addition to determinants of resistance to chemtoherapy, a resistance plasmid of the hospital strain of Prtoeus rettgeri from the Munich Hospital area also carries information on resistance to mercury ions. At the same time strains with this R-factor are more insensitive to phenylmercuric borate, the active principle of the widely used disinfectant Merfer. This significance of the widely used disinfectant Merfer. This significance of this resistance to disinfectants for the appearance of the local hospital strain of Proteus rettgeri is discussed. Moreover, the far-reaching risks of the selection of chemotherapy-resistant bacterial strains by disinfectants with reduced activity against bacteria resistant to chemotherapy are pointed out. Therefore, it is recommended to abandon the use of mercury as an active principle of disinfectants.
除了对化疗的耐药决定因素外，来自慕尼黑医院地区的雷氏普罗威登斯菌医院菌株的耐药质粒还携带对汞离子的耐药信息。同时，带有这种R因子的菌株对苯基汞硼酸盐（广泛使用的消毒剂Merfer的活性成分）更不敏感。本文讨论了这种对消毒剂的耐药性对于雷氏普罗威登斯菌当地医院菌株出现的意义。此外，还指出了使用对耐化疗细菌活性降低的消毒剂来选择耐化疗细菌菌株所带来的深远风险。因此，建议放弃使用汞作为消毒剂的活性成分。
