van Miert A S, van Soeren J H, Hagens F M
Tijdschr Diergeneeskd. 1976 Aug 15;101(16):905-11.
In addition to the antimycotic antibiotics described in a previous paper (Tijdschr. Diergeneesk., 101, 900-904, (1976)), the drugs used in the treatment of dermatomycosis include a fairly large number of synthtic compounds showing a wide variety of chemical structures. These are partly old and occasionally even obsolete agents (often in use as early as prior to 1945); a number of these drugs are of more recent date. They will be discussed in the present paper. So far as is known, the physicochemical and pharmacotoxicological properties, antifungal range, mechanisms of action and preparations will be reviewed.
除了在前一篇论文(《荷兰兽医杂志》,101, 900 - 904, (1976))中描述的抗真菌抗生素外,用于治疗皮肤真菌病的药物还包括相当多具有多种化学结构的合成化合物。这些药物部分是旧药,甚至偶尔是已淘汰的药物(早在1945年之前就经常使用);其中一些药物是较新的。本文将对它们进行讨论。就目前所知,将对其理化性质、药物毒理学性质、抗真菌范围、作用机制及制剂进行综述。