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低剂量阿司匹林用于卒中二级预防

[Low dose acetylsalicylic acid in secondary prevention of stroke].

作者信息

Deecke L, Zeiler K

机构信息

Neurologische Universitätsklinik, Wien.

出版信息

Wien Klin Wochenschr. 1993;105(17):485-7.

PMID:8212707
Abstract

Acetylsalicylic acid (ASA) as secondary prophylaxis after ischaemic cerebrovascular events is well established and its efficacy unquestioned since over 15 years. According to the results of two European studies a dose of 100 mg per day is sufficient to reduce the incidence of further stroke, myocardial infarction, and death due to cardiovascular causes. This satisfactory response to low-dose ASA applies to patients with transient ischaemic attacks, reversible ischaemic events, and minor strokes. In cases with severe cardiac disease, however, a high dosage of ASA or anticoagulation therapy may be necessary to prevent further vascular events.

摘要

阿司匹林(ASA)作为缺血性脑血管事件后的二级预防药物已被广泛应用超过15年,其疗效毋庸置疑。根据两项欧洲研究的结果,每天100毫克的剂量足以降低因心血管原因导致的再次中风、心肌梗死和死亡的发生率。低剂量ASA对短暂性脑缺血发作、可逆性缺血事件和轻度中风患者有令人满意的疗效。然而,对于患有严重心脏病的患者,可能需要高剂量的ASA或抗凝治疗以预防进一步的血管事件。

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