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[人脑丘脑 - 下丘脑结构参与病理过程的电生理关联]

[The electrophysiological correlates of the involvement in a pathological process of the thalamo-hypothalamic structures of the human brain].

作者信息

Boldyreva G N, Bragina N N

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Jul-Aug;43(4):721-9.

PMID:8212873
Abstract

Comparative EEG studies (with the normative data control) were carried out in patients with different anatomic-topographical variants of craniopharyngioma, effecting the hypothalamus (12 patients) and involving thalamo-subcortical structures in the pathological process (17 patients). Characteristics of EEG reorganization were found to be determined in the first instance by the stage of development of the focal process. Analysis of the regional characteristics and intercentral relations of the brain biopotentials revealed besides the common features, the differences in the effects of certain diencephalic structures on the spatial-temporal EEG organization. Hypothalamic areas exert mainly global influence on the EEG pattern formation. Thalamic structures influence genesis of the rhythmic activity forms and their intercentral relations more differentially and make more important contribution to the formation of the balanced (in norm) pattern of the brain electrical processes spatial-temporal organization.

摘要

对患有不同解剖-地形变异的颅咽管瘤患者进行了对比脑电图研究(以正常数据作为对照),这些变异影响下丘脑(12例患者)且病理过程累及丘脑-皮质下结构(17例患者)。结果发现,脑电图重组的特征首先由局灶性病变的发展阶段决定。对脑生物电位的区域特征和中枢间关系进行分析后发现,除了共同特征外,某些间脑结构对脑电图时空组织的影响也存在差异。下丘脑区域主要对脑电图模式形成产生整体影响。丘脑结构对节律性活动形式的产生及其中枢间关系的影响更为不同,并对正常情况下大脑电活动时空组织平衡模式的形成做出更重要的贡献。

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