Clevens R A, Esclamado R M, Hartshorn D O, Lewin J S
Department of Otolaryngology-Head and Neck Surgery, University of Michigan Hospitals, Ann Arbor.
Ann Otol Rhinol Laryngol. 1993 Oct;102(10):792-6. doi: 10.1177/000348949310201010.
The successful production of voice with a tracheoesophageal puncture (TEP) and voice prosthesis requires a compliant pharyngoesophageal segment. Speech failure is commonly attributed to spasm of the pharyngoesophageal segment. During total laryngectomy (TL), a 3-layer closure is typically performed. This prospective single-arm study examines the safety and efficacy of TL and TEP with nonclosure of the pharyngeal musculature to prevent pharyngoesophageal spasm as an alternative to 3-layer closure with pharyngeal plexus neurectomy and/or pharyngeal constrictor myotomy. Twenty-one consecutive patients were enrolled by a single surgeon. The mean duration of follow-up was 19.5 +/- 7.9 months. Surgical complications and voice rehabilitation outcomes were examined. An overall complication rate of 28.5% was observed. Fluency was achieved in 75% of patients within a mean of 4.3 +/- 5.1 months. Speech failure was attributable to early primary site and neck recurrence (5%), hypoglossal nerve palsy (5%), hypopharyngeal stricture and recurrence (5%), dementia (5%), and intransigent alcohol abuse (5%). Pharyngoesophageal spasm was not observed in any subjects. We conclude that primary TEP with nonclosure of the pharyngeal muscle during TL is relatively safe. Furthermore, it is preferable over 3-layer closure because it avoids pharyngoesophageal spasm, a factor limiting voice rehabilitation.
通过气管食管穿刺(TEP)和语音假体成功产生语音需要一个顺应性良好的咽食管段。语音失败通常归因于咽食管段痉挛。在全喉切除术(TL)期间,通常进行三层缝合。这项前瞻性单臂研究探讨了在不缝合咽肌组织的情况下进行TL和TEP以预防咽食管痉挛的安全性和有效性,作为采用咽丛神经切除术和/或咽缩肌肌切开术的三层缝合的替代方法。由一名外科医生连续纳入21例患者。平均随访时间为19.5±7.9个月。检查手术并发症和语音康复结果。观察到总体并发症发生率为28.5%。75%的患者在平均4.3±5.1个月内实现了流畅发音。语音失败归因于早期原发部位和颈部复发(5%)、舌下神经麻痹(5%)、下咽狭窄和复发(5%)、痴呆(5%)以及顽固的酒精滥用(5%)。在任何受试者中均未观察到咽食管痉挛。我们得出结论,在TL期间不缝合咽肌进行原发性TEP相对安全。此外,它优于三层缝合,因为它避免了咽食管痉挛,而咽食管痉挛是限制语音康复的一个因素。