An atypical carcinoid tumor of the lung with mutations in the p53 gene and the retinoblastoma gene.
作者信息
Hiyama K, Hasegawa K, Ishioka S, Takahashi N, Yamakido M
机构信息
Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
出版信息
Chest. 1993 Nov;104(5):1606-7. doi: 10.1378/chest.104.5.1606.
PMID:8222834
Abstract
Molecular analysis of a metastatic lesion of an atypical carcinoid tumor of the lung obtained from a 77-year-old man at autopsy revealed a point mutation in the p53 gene and a deletion in the retinoblastoma (Rb) mRNA. This case suggests that both these antioncogenes may be involved in the progression of atypical carcinoid tumor.
摘要
Zotero 插件