Mukai H, Minemawari Y, Hanawa N, Mita T, Motoe M, Nakata T
Department of Cardiology, Teine Keijinkai Hospital, Japan.
Jpn Circ J. 1993 Oct;57(10):1021-6. doi: 10.1253/jcj.57.1021.
We present a 46-year-old male with unstable angina and bilateral coronary-to-pulmonary artery fistulae in whom reversible myocardial ischemia was detected by exercise-stress thallium-201 single-photon emission computed tomography (SPECT). Coronary angiography revealed a 99% stenosis at the proximal site of the left descending coronary artery and bilateral coronary-to-pulmonary artery fistulae with a saccular aneurysm. Percutaneous transluminal coronary angioplasty abolished chest pain and electrocardiographic changes. However, definitely improved, but still present, stress-induced perfusion abnormalities were demonstrated by an exercise-stress thallium-201 SPECT study. Myocardial ischemia was the only serious complication related to the coronary fistulae, and after they were surgically resected, the reversible perfusion abnormality was no longer observed. These findings suggest that coronary-to-pulmonary artery fistulae potentiated the myocardial ischemia in patient with coronary stenosis leading to unstable angina and prolonged the presence of coronary perfusion abnormality on stress thallium scans probably through a coronary steal phenomenon.
我们报告一名46岁男性,患有不稳定型心绞痛和双侧冠状动脉-肺动脉瘘,通过运动负荷铊-201单光子发射计算机断层扫描(SPECT)检测到可逆性心肌缺血。冠状动脉造影显示左冠状动脉前降支近端99%狭窄,双侧冠状动脉-肺动脉瘘并伴有囊状动脉瘤。经皮冠状动脉腔内血管成形术消除了胸痛和心电图改变。然而,运动负荷铊-201 SPECT研究显示,应激诱导的灌注异常虽有明显改善但仍存在。心肌缺血是与冠状动脉瘘相关的唯一严重并发症,手术切除冠状动脉瘘后,不再观察到可逆性灌注异常。这些发现表明,冠状动脉-肺动脉瘘使患有冠状动脉狭窄导致不稳定型心绞痛的患者心肌缺血加重,并可能通过冠状动脉窃血现象延长应激铊扫描时冠状动脉灌注异常的存在时间。