Quirk J A, Kendall B, Kingsley D P, Boyd S G, Pitt M C
Department of Clinical Neurophysiology, Hospital for Sick Children, London, U.K.
Neuropediatrics. 1993 Aug;24(4):193-9. doi: 10.1055/s-2008-1071538.
Two distinctive electroencephalographic abnormalities, very high amplitude rhythmic activity or prominent fast activity, have been described in children with extensive cortical dysplasia. Cases with cortical dysplasia identified on computerised tomography or magnetic resonance imaging, or a characteristic EEG were selected. One hundred and forty electroencephalograms from 94 cases were reviewed and related to the imaging findings. An EEG with very high amplitude rhythmic activity was found to have high specificity for severe cortical dysplasia but low sensitivity (< 50% cases). Abnormal fast activity was not specific and was seen with very diverse pathologies. The EEG features of most cases with localised cortical dysplasia were very variable. The EEG could be normal even when the cortical dysplasia was extensive.
在患有广泛性皮质发育异常的儿童中,已描述出两种独特的脑电图异常,即非常高幅的节律性活动或显著的快速活动。选择了在计算机断层扫描或磁共振成像上发现皮质发育异常或具有特征性脑电图的病例。回顾了94例患者的140份脑电图,并将其与影像学结果相关联。发现具有非常高幅节律性活动的脑电图对严重皮质发育异常具有高特异性,但敏感性较低(<50%的病例)。异常快速活动不具有特异性,在多种不同病变中均可出现。大多数局限性皮质发育异常病例的脑电图特征变化很大。即使皮质发育异常广泛,脑电图也可能正常。