Tien R D, Felsberg G J, Campi de Castro C, Osumi A K, Lewis D V, Friedman A H, Crain B, Radtke R A
Department of Radiology, Duke University Medical Center, Durham, NC 27710.
Radiology. 1993 Dec;189(3):835-42. doi: 10.1148/radiology.189.3.8234712.
This study was performed to determine the sensitivity and specificity of fast spin-echo (FSE) magnetic resonance (MR) imaging in detecting mesial temporal sclerosis.
Twenty-one patients with a diagnosis of complex partial seizures were studied. Criteria for abnormality included visual detection of hippocampal MR signal abnormality and atrophy or significantly decreased hippocampal volume determined by using MR morphometric techniques.
The overall sensitivity and specificity of MR imaging in demonstrating correct lateralization of seizure focus were both 100%. The positive predictive value of FSE MR imaging was 100%. The negative predictive value was 50%.
The authors recommend FSE MR imaging of the hippocampus as the imaging technique of choice in the evaluation of patients with complex partial seizures for mesial temporal sclerosis.
本研究旨在确定快速自旋回波（FSE）磁共振（MR）成像检测内侧颞叶硬化的敏感性和特异性。
对21例诊断为复杂部分性癫痫的患者进行研究。异常标准包括肉眼观察海马MR信号异常以及使用MR形态测量技术确定的海马萎缩或体积显著减小。
MR成像在显示癫痫病灶正确定位方面的总体敏感性和特异性均为100%。FSE MR成像的阳性预测值为100%。阴性预测值为50%。
作者推荐对海马进行FSE MR成像，作为评估复杂部分性癫痫患者内侧颞叶硬化的首选成像技术。
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