Willner J, Kiricuta I C, Kölbl O, Bohndorf W
Klinik und Poliklinik für Strahlentherapie, Universität Würzburg.
Zentralbl Chir. 1993;118(9):525-31.
Prognostic factors in breast cancer have been frequently discussed in the oncologic literature. We reviewed our data of 795 patients who were referred to the Department of Radiation Oncology of the University of Wuerzburg between 1978 and 1988 in order to find out, whether the well known and proven prognostic factors in breast cancer were sufficiently in use in clinical routine, even out of university oncologic centres. We found, that beside of determination of the histological tumor-type the assessment of tumor size (= pT-status) and axillary (= pN-)status is performed nowadays in all patients. In contrary, the determination of the hormonal receptor status (HRS) had a slow beginning. From 1980 the rate of determinated HRS arose from 5% to 80% nowadays. The demand of removal and examination of at least 12 axillary lymph nodes in axillary dissection in order to determine correctly the axillary status is not yet part of the oncological routine. In 1988 in only 40% of the referred patients axillary diagnosis was done in a manner corresponding to international rules.
乳腺癌的预后因素在肿瘤学文献中已被频繁讨论。我们回顾了1978年至1988年间转诊至维尔茨堡大学放射肿瘤学系的795例患者的数据,以查明,即使在大学肿瘤中心之外,乳腺癌中众所周知且已得到证实的预后因素在临床常规中是否得到充分应用。我们发现,如今在所有患者中,除了确定组织学肿瘤类型外,还会对肿瘤大小(=pT状态)和腋窝(=pN -)状态进行评估。相反,激素受体状态(HRS)的确定起步较晚。从1980年起,如今已确定HRS的比例从5%上升到了80%。为了正确确定腋窝状态,在腋窝清扫术中至少切除并检查12个腋窝淋巴结的要求尚未成为肿瘤学常规的一部分。1988年,在转诊患者中,只有40%的腋窝诊断是按照国际规则进行的。