Kim K M, Choi H
Department of Urology, Seoul National University Children's Hospital, Korea.
J Korean Med Sci. 1993 Jun;8(3):197-201. doi: 10.3346/jkms.1993.8.3.197.
Urodynamic evaluation in pediatric neurogenic bladder is prerequisite for accurate prediction of prognosis and selection of appropriate treatment modality. We classified normal, hyperreflexic and areflexic bladders by cystometry. Hyperreflexic bladder was subdivided into two groups with or without detrusor sphincter dyssynergia and areflexic bladder into low pressure and high pressure. Among 36 patients with myelodysplasia on whom we performed a videourodynamic study vesicoureteral reflux was found in three of 7 patients with hyperreflexia with detrusor sphincter dyssynergia, two of 6 patients with hyperreflexia without detrusor sphincter dyssynergia and five of 10 patients with areflexia with high pressure. Low pressure areflexic bladder didn't show vesicoureteral reflux. When we evaluated 39 pediatric neurogenic bladder patients with a mean 25.5 follow-up months period, upper tract deterioration was improved and normal findings persisted in all the compliant patients to treatment. In the noncompliant group initial abnormal upper tract findings persisted or aggravated, especially in hyperreflexic bladder with dyssynergia and high pressure areflexic bladder. One of the three hyperreflexic bladders with dyssynergia and two of six high pressure areflexic bladders received augmented cystoplasty. These data show that urodynamic evaluation in pediatric neurogenic bladder provides excellent criteria for selecting high risk groups in pediatric neurogenic bladder.
小儿神经源性膀胱的尿动力学评估是准确预测预后和选择合适治疗方式的前提。我们通过膀胱测压将膀胱分为正常、反射亢进和无反射三类。反射亢进性膀胱又细分为伴有或不伴有逼尿肌括约肌协同失调的两组,无反射性膀胱分为低压和高压两类。在我们对36例脊髓发育不良患者进行影像尿动力学检查的过程中,发现7例伴有逼尿肌括约肌协同失调的反射亢进患者中有3例存在膀胱输尿管反流,6例不伴有逼尿肌括约肌协同失调的反射亢进患者中有2例存在反流,10例高压性无反射患者中有5例存在反流。低压性无反射膀胱未出现膀胱输尿管反流。当我们对39例小儿神经源性膀胱患者进行平均25.5个月的随访评估时,所有依从治疗的患者上尿路病变均得到改善且保持正常表现。在不依从组中,最初的上尿路异常表现持续存在或加重,尤其是伴有协同失调的反射亢进性膀胱和高压性无反射膀胱。3例伴有协同失调的反射亢进性膀胱中有1例以及6例高压性无反射膀胱中有2例接受了膀胱扩大术。这些数据表明,小儿神经源性膀胱的尿动力学评估为选择小儿神经源性膀胱的高危人群提供了良好的标准。