Franĕk F, Wasserman R L, Novotny J, Kehoe J M
Eur J Immunol. 1976 Jun;5(6):427-9. doi: 10.1002/eji.1830050614.
Pig gamma-chains contain a significant fraction of the unblocked VHIII variable region subgroup. The amino terminal sequence (30 residues) was found to be uniform and more than 90% homologous with the prototype sequence of the human VHIII subgroup. An additional VHIII phylogenetically associated residue, glutamic acid in position 2 was identified in these porcine heavy chains.
猪γ链包含相当一部分未封闭的VHIII可变区亚组。发现其氨基末端序列(30个残基)是一致的,并且与人类VHIII亚组的原型序列有超过90%的同源性。在这些猪重链中还鉴定出了另一个在系统发育上与VHIII相关的残基,即第2位的谷氨酸。