[Effect of many years of hemodialysis therapy on FSH secretion induced by luliberin in men with chronic renal failure].

The purpose of the work was an explanation, what was the influence of many years of hemodialysis therapy on FSH secretion in men with chronic renal failure (CRF). The studies were carried out in 41 men with CRF treated with haemodialysis, 10 men with advanced CRF who were not dialysed, and in 15 healthy men. In all studied individuals the luliberin stimulation test (LH-RH) was performed. It was found that men with CRF, independently of the duration of hemodialysis therapy, were characterized by increased serum FSH concentration in comparison to healthy subjects. In men dialysed form over 50 months, the FSH concentration was higher than in those dialysed for a shorter time period, and not dialysed. The reaction of FSH secretion stimulated by LH-RH in men dialysed for less than 100 months and not dialysed was diminished while in those dialysed for over 100 months it was normalized.