躁狂症患者地塞米松后的皮质醇水平及计算机断层扫描结果

Post-dexamethasone cortisol levels and computerized tomographic findings in manic patients.

作者信息

Mukherjee S, Schnur D B, Lo E S, Sackeim H A, Cooper T B

机构信息

Department of Psychiatry, Medical College of Georgia, Augusta 30912-3800.

出版信息

Acta Psychiatr Scand. 1993 Sep;88(3):145-8. doi: 10.1111/j.1600-0447.1993.tb03429.x.

DOI:10.1111/j.1600-0447.1993.tb03429.x

PMID:8249643

Abstract

The relations of post-dexamethasone cortisol levels to computerized tomography (CT) scan findings of lateral and third ventricle size and cortical sulcal prominence rated separately for frontal and parieto-occipital distributions were examined in 15 manic patients. Failure to suppress endogenous cortisol after a dexamethasone challenge was associated with larger third ventricles, but not to any of the other CT scan measures.

摘要

对15名躁狂症患者进行了研究，以检查地塞米松后皮质醇水平与计算机断层扫描（CT）结果之间的关系，这些结果分别针对额叶和顶枕叶分布的外侧和第三脑室大小以及皮质沟回突出程度进行评级。地塞米松激发试验后内源性皮质醇未能被抑制与第三脑室较大有关，但与其他任何CT扫描测量结果均无关。