Smith F C, Grimshaw G M, Paterson I S, Shearman C P, Hamer J D
Department of Vascular Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Br J Surg. 1993 Nov;80(11):1406-9. doi: 10.1002/bjs.1800801117.
As part of the Birmingham Community Aneurysm Screening Project, 3500 men aged 65-75 years from 20 urban general practices were invited for aortic ultrasonographic screening at their own general practitioner's surgery; 2669 (76.3 per cent) attended. Compliance rates varied between catchment areas, from 52.1 per cent for inner-city areas to 89.6 per cent for suburbs. Successful aortic imaging was achieved in 97.3 per cent of scans. Aortic diameter > 29 mm occurred in 219 patients (8.4 per cent) and 79 (3.0 per cent) with a diameter > 40 mm were referred for vascular surgical assessment; 140 patients with an aortic diameter of 29-40 mm are currently undergoing follow-up by serial ultrasonographic examinations at intervals of 3 months at their doctor's surgery. Risk factor analysis revealed ischaemic heart disease in 21.9 per cent of men with aneurysm, compared with 11.6 per cent in those without (P < 0.001); 18.3 per cent of men with aneurysm had had a previous myocardial infarction and 13.2 per cent had peripheral vascular disease, compared with 7.4 per cent (P < 0.001) and 8.0 per cent (P < 0.01) respectively of those without. No association was found between aneurysm and hypertension or diabetes. Community-based aortic screening is an inexpensive, effective method of diagnosis of aneurysm, with high compliance from the at-risk cohort of an urban population. Such screening programmes may help to reduce the mortality rate from aortic aneurysm rupture.
作为伯明翰社区动脉瘤筛查项目的一部分,来自20家城市全科诊所的3500名65至75岁男性被邀请到他们自己的全科医生诊所进行主动脉超声筛查;2669人(76.3%)参加了筛查。不同集水区的依从率有所不同,市中心城区为52.1%,郊区为89.6%。97.3%的扫描成功完成了主动脉成像。219名患者(8.4%)的主动脉直径>29 mm,79名(3.0%)直径>40 mm的患者被转诊进行血管外科评估;140名主动脉直径在29至40 mm之间的患者目前正在其医生诊所每隔3个月进行一次超声检查随访。危险因素分析显示,患有动脉瘤的男性中21.9%有缺血性心脏病,而未患动脉瘤的男性中这一比例为11.6%(P<0.001);患有动脉瘤的男性中18.3%曾有过心肌梗死,13.2%有外周血管疾病,而未患动脉瘤的男性中这一比例分别为7.4%(P<0.001)和8.0%(P<0.01)。未发现动脉瘤与高血压或糖尿病之间存在关联。基于社区的主动脉筛查是一种廉价、有效的动脉瘤诊断方法,城市高危人群的依从性很高。此类筛查项目可能有助于降低主动脉瘤破裂的死亡率。