Karlson K H, Pickert C B, Schexnayder S M, Heulitt M J
Section of Pulmonology, University of Arkansas for Medical Sciences, Little Rock.
Pediatr Pulmonol. 1993 Oct;16(4):215-8. doi: 10.1002/ppul.1950160402.
Bleeding is one of the most feared complications of veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO), and is also a potential complication of flexible fiberoptic bronchoscopy (FFB). We retrospectively reviewed 14 patients who underwent FFB procedures with bronchial washings (BW) and bronchoalveolar lavage (BAL) to evaluate the safety of this procedure in children on ECMO. Standard FFB with BAL/BW technique was used after stabilization on ECMO. Three patients underwent two procedures each, and one patient underwent three, for a total of 19 procedures. No significant complications, such as bleeding have occurred. Three patients required additional ECMO support shortly after FFB. After the 16 procedures done for atelectasis, seven patients improved radiographically, three had increased opacifications, and six were unchanged. The remaining three patients had suspected pulmonary infections, and in each, therapeutic decisions were guided by the BAL results. Lung compliance was unchanged or improved after 11 of 13 procedures. We conclude that FFB with BAL/BW in children on ECMO is safe and may benefit certain patients.
出血是静脉 - 动脉(V - A)体外膜肺氧合(ECMO)最令人担忧的并发症之一,也是可弯曲纤维支气管镜检查(FFB)的潜在并发症。我们回顾性分析了14例接受FFB检查并进行支气管灌洗(BW)和支气管肺泡灌洗(BAL)的患者,以评估该检查在接受ECMO治疗的儿童中的安全性。在ECMO治疗稳定后采用标准的FFB联合BAL/BW技术。3例患者各接受了2次检查,1例患者接受了3次检查,共进行了19次检查。未发生出血等严重并发症。3例患者在FFB检查后不久需要额外的ECMO支持。针对肺不张进行的16次检查后,7例患者的影像学表现有所改善,3例患者的肺部阴影增加,6例患者无变化。其余3例患者疑似肺部感染,每例患者的治疗决策均根据BAL结果做出。13次检查中的11次检查后肺顺应性未变或有所改善。我们得出结论,在接受ECMO治疗的儿童中进行FFB联合BAL/BW检查是安全的,并且可能使某些患者受益。