Kreiborg S, Dahl E
Department of Pediatric Dentistry, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark.
Am J Med Genet. 1993 Oct 1;47(5):753-60. doi: 10.1002/ajmg.1320470531.
Using longitudinal roentgencephalometry, we studied craniofacial growth in two children with mandibulofacial dysostosis. In one child, data were supplemented by three-dimensional reconstructions of CT scans and stereolithographic models of the craniofacial skeleton. Progressive basilar kyphosis was found in both children, the hypothesized caused being bending of the cranial base at the level of the sphenofrontal suture. Such bending acting in concert with abnormal growth of the mandible led to impairment of the airway. We advocate careful monitoring of craniofacial growth and respiratory function in mandibulofacial dysostosis from birth through adolescence.
我们使用纵向头颅X线测量法，研究了两名下颌面部发育不全患儿的颅面生长情况。在一名患儿中，通过CT扫描的三维重建和颅面骨骼的立体光刻模型补充了数据。两名患儿均发现有进行性基底后凸，推测其原因是颅底在蝶额缝水平弯曲。这种弯曲与下颌骨的异常生长共同作用导致气道受损。我们主张从出生到青春期对下颌面部发育不全患儿的颅面生长和呼吸功能进行仔细监测。
