碘酸盐对猫视网膜电图视网膜内b波和c波的影响。

Effects of iodate on intraretinal b and c waves of the cat electroretinogram.

作者信息

Yamamoto F, Kiryu J, Hiroi K

机构信息

Department of Ophthalmology, Faculty of Medicine, Kyoto University, Japan.

出版信息

Ophthalmologica. 1993;206(3):152-7. doi: 10.1159/000310382.

DOI:10.1159/000310382

PMID:8272338

Abstract

In 12 cats, the intravenous and intravitreal administrations of sodium iodate (SI) were performed to examine the effects on b and c waves of electroretinogram in the dark-adapted retina. The intravitreal SI (0.5-3.5 mM) produced the complete suppression of intraretinal b waves without remarkable changes of slow PIII and light-evoked [K+]o decrease in the subretinal space. Intravenous SI (30 mg/kg) also showed the suppression of intraretinal b waves. SI not only acted as a poison to the retinal pigment epithelium but also might block the post-synaptic response.

摘要

在12只猫中，进行了碘酸钠（SI）的静脉内和玻璃体内给药，以检查对暗适应视网膜电图的b波和c波的影响。玻璃体内注射SI（0.5 - 3.5 mM）可完全抑制视网膜内的b波，而视网膜下间隙中缓慢的PIII和光诱发的[K +]o降低没有明显变化。静脉注射SI（30 mg/kg）也显示出对视网膜内b波的抑制作用。SI不仅对视网膜色素上皮起毒害作用，还可能阻断突触后反应。